Page 8 of 20 · 476 questions tagged content-assay.
For reference: deamidation · survodutide · 25 °C. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review…
Details up front: hydrolysis · dulaglutide · 4 °C. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…
What I have: racemisation · orforglipron · 37 °C. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know…
Concretely: QST · tirzepatide. I have two candidate explanations and no way to distinguish them. The same procedure has worked without incident several times…
The case in front of me: peptide mapping · survodutide. I would like to define my thresholds before I have a result, for obvious reasons. I want a plan with explicit…
Stated plainly: 5 mg · a GLP-1 receptor agonist. The units are where I keep going wrong, so please be explicit about them. I have sanity-checked the order of…
What I am working with: JEEP · orforglipron. Before I write this off, I want to check whether it is a known failure mode. I have the lot number, the certificate and…
The case in front of me: 10 mg · tirzepatide. Please show the division. I want to check my own against yours. I would like the general form as well as the specific…
What I have: GGPeps · semaglutide. An unexpected observation, and I would like a differential rather than reassurance. The conditions were within what I understood to…
The specifics, since they change the answer: 4 mg · semaglutide. I would like the arithmetic checked rather than the conclusion asserted. I have deliberately not used…
The case in front of me: HJ · tirzepatide. I think I have a problem. I am not yet sure whether it is a real problem or a measurement artefact. I want to know whether…
Details up front: hydrolysis · retatrutide · 4 °C. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…
Setup, so nobody has to ask: aggregation · mazdutide · 30 °C. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows,…
For reference: 4 mg · survodutide. I would rather understand the derivation than memorise the outcome. Two people I asked gave two answers that differ by a factor of…
The case in front of me: 40 mg · oral semaglutide. I want the working, not the result — I need to be able to redo it with different numbers. I care about the…
What I am working with: 60 mg · mazdutide. I have worked this out and I would like someone to find the error, because I suspect there is one. My working so far, for…
What I am working with: a Karl Fischer water content test · liraglutide. These are treated as interchangeable and I do not think they are. If both are acceptable I…
Concretely: GGPeps · semaglutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
I have the report as a PDF with the chromatogram on page two, so I can quote specifics. I can predict the outcome but I cannot explain it, which means I will get the…
Stated plainly: 98.2% · cagrilintide · Homopeptide. I would like to set this up properly once, rather than adjust it repeatedly. My budget is real but not tight, and…
Numbers first: hydrolysis · dulaglutide · 37 °C. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer.…
The case in front of me: JEEP · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
Concretely: WWB · orforglipron. Before I write this off, I want to check whether it is a known failure mode. I have the lot number, the certificate and the date, and…
Conditions: 98.8% · liraglutide · BCH. I want to decide this in advance so that I am not deciding it under pressure later. Assume I will follow the plan I write down,…