Page 2 of 3 · 56 questions tagged mash.
Details up front: triglycerides · survodutide. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried…
Following on from the discussion of sampling variability: if simultaneous biopsies from the same liver disagree by a fibrosis stage in a meaningful fraction of cases,…
What I have: albumin-to-creatinine ratio · orforglipron. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…
Concretely: lipase · mazdutide. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear that than…
What I have: creatinine · cagrilintide. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
Conditions: GGT · liraglutide. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
What I have: AST · survodutide. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to reason it…
Conditions: eGFR · retatrutide. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how confident the…
The particulars: LDL-C · mazdutide. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My background is…
Details up front: AST · ecnoglutide. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to reason…
The specifics, since they change the answer: GGT · tirzepatide. I want to know whether this is a real physical effect or an artefact of how it is measured. What…
Concretely: HbA1c · oral semaglutide. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically, because…
What I have: ferritin · tirzepatide. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
The case in front of me: AST · semaglutide. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to…
Stated plainly: magnesium · liraglutide. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically,…
Details up front: creatinine · mazdutide. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
Setup, so nobody has to ask: ALT · a GLP-1 receptor agonist. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me…
I have three data points across nine months, which I hope is enough to see a trend. The comparison I want does not seem to exist anywhere in a form I can evaluate. I…
Details up front: ApoB · dulaglutide. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I would…
Details up front: ApoB · orforglipron. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I would…
For reference: TSH · orforglipron. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how confident…
I have three data points across nine months, which I hope is enough to see a trend. I suspect the usual explanation for this is wrong, or at least incomplete. I am…
This matters because it predicts what a related molecule should do. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume…
Concretely: albumin-to-creatinine ratio · retatrutide. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…