Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement artefacts as often as findings, and what mitigates it.
The trend is what I care about; individual weeks are obviously noise. I want to understand what this actually establishes, as opposed to what it is being used to…
The particulars: semaglutide · STEP 2. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable…
I want the floor, not the optimum. I am losing about 0.9 kg a week on tirzepatide and I have limited capacity to train: realistically two sessions a week, 40 minutes…
Intake is tracked, imperfectly, and I am aware of the direction of the error. I suspect the honest answer is that it depends, in which case I would like to know on…
The case in front of me: semaglutide · SUSTAIN-6. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…
Concretely: tirzepatide · SURPASS-3. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
I would like to know what to measure as much as what to do. Both of these get recommended confidently by different people, which suggests neither is obviously right.…
Stated plainly: oral semaglutide · SOUL. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
The trend is what I care about; individual weeks are obviously noise. I have used one of these for a while and I am considering switching, which requires a reason.…
I have measured myself three ways inside eight days and got three different stories, and I would like to understand which one to believe before I change anything…
What I have: semaglutide · STEP 5. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
Stated plainly: semaglutide · STEP 1. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline. I do…
What I have: a GLP-1 receptor agonist · STEP 5. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
Eleven months, 18 kg down. My creatinine has fallen from 1.05 to 0.96 mg/dL and the reported eGFR has gone from 85 to 95. I would like to believe my kidneys have…
The trend is what I care about; individual weeks are obviously noise. I want to know what the trade-off actually is rather than which option is fashionable. I would…
Scale weight, waist circumference and a repetition maximum, all logged weekly. I suspect the honest answer is that it depends, in which case I would like to know on…
Stated plainly: tirzepatide · SURPASS-2. I would like help reading this properly rather than being told what conclusion to reach. I have the full report including the…
I would like to know what to measure as much as what to do. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to…
Conditions: retatrutide · TRIUMPH-3. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
The specifics, since they change the answer: semaglutide · STEP 4. I have the document in front of me and I can read the numbers. What I cannot do is interpret them.…
I have three DEXA scans on the same scanner at twelve-week intervals, fasted, same time of day. I suspect the usual explanation for this is wrong, or at least…
Scale weight, waist circumference and a repetition maximum, all logged weekly. I have read the primary source rather than the summary, which has left me with more…
The trend is what I care about; individual weeks are obviously noise. I would rather over-plan the first cycle and simplify later. I am prepared to do the work if…
The trend is what I care about; individual weeks are obviously noise. I am trying to choose between two options that are usually discussed as though only one exists.…
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